Vitamin E Levels in People With both well-controlled and poorly-controlled typr 2 diabetes

: History: Increased oxidative stress and decreased antioxidant are linked to diabetes type 2 Diabetes In diabetic people, vitamin E administration lowers oxidative stress. We aimed to gauge the amount of this vitamin using these techniques:By planning the current study, patients will be able to evaluate its impact on patient-controlled diabetes. This descriptive and cross-sectional research, which involved 186 individuals with type 2 diabetes, was conducted. Patients were put into two groups 1 depending on whether their HbA1C levels were less than or greater than 7 (measured using the HPLC technique), as well as the levels of TG, cholesterol, HDL


INTRODUCTION
Insulin is a condition that is on the rise throughout.The prevalence of diabetes is increasing worldwide, especially in poorer nations.1In Iran, there are 7.5 million diabetes people as of right now. 2 The number of people with diabetes worldwide has significantly grown during the past 20 years, rising from 30 million as of 2010 to 285 million in 1985.If the current trend keeps going, the diabetes international federation estimates that there will be 438 million diabetic people globally in 2030.Even if type 1 and type 2 diabetes are growing increasingly widespread globally.Type 2 diabetes,3 however, is spreading far more fast than type 1.This phenomenon undoubtedly has a number of contributing elements, including the growth in obesity and the fall in physical activity.In both men and women, the frequency of this condition is about the same across all age groups (11.8% in males over 20 Global estimates indicate that the majority of diabetes will be between the ages of 45 and 64 in 2030 (10.8% in women over 20   The source based on Table No. -2-Table 3: Effects of caloric, amino acids, and fat intake in diabetic patients.
In the existing study 186 diabetic patients were examined.
From within examined patients, 129 (69.3%) were women 53.33 11.2.158 (84.9%) of the 186 patients were city dwellers, 28 (15.1) were from rural areas, and 171 (91.9%) were to Ardabil.The findings revealed that 114 patients' (61.3%) sole method of blood sugar management was insulin.The remainder (51.6%) of the patients did not use lipid-lowering medications, whereas 90 patients (48.4%) did.The findings indicated that 144 individuals (77.4%) had a family history of diabetes type 2 that was positive.And 2 patients (1%) had a history of type 1 diabetes, with an average lifespan of 8.46.6 years for patients.Additionally, the patients' average BMI was 28.324.1 kg/m2.According to the findings, patients' average blood sugar levels were 217.5100.5 mg/dl.lowest blood sugar level. 8 Mean AST values in patients were 26.6417.2IU/l and 25.7816.2IU/L,respectively (Table 2).Table 3 summarizes the patients' calorie, protein, and fat intake levels. 9Additionally, the average amount of vitamin E consumed by diabetes individuals was 4.53 to 4.24 nmol/l.The average amount of food consumed by patients was 1277.4337.01gr.Based on HBA1C levels, patients were split into two groups: those with levels that were equal to or less than 7 (managed) and those with levels that were greater than 7 (uncontrolled).A total of 97 individuals (52.2%) had their diabetes under control at this stage, while the remaining diabetics were uncontrolled.
Figure .-2 Outcomes of hepatic enzyme testing in patients with diabetes

Table -1-Results of the lipid profile in diabetic individuals are shown in. diabetes
Data were gathered, coded, and processed into the statistical program SPSS V16.Following the use of analytical statistical techniques like the t-test and Pierson statistical exam, descriptive methods of statistical analysis were used to examine the data.The test error significance for confidence level was 0.95 smaller than 0.05 in all tests stated.Information was kept private, and results were reported confidentially in compliance with medical ethical standards.Study constraints were patient refusal of assisting with testing, expensive test fees,7 and patient overdose on vitamin supplements.
mellitus's lipid profiles were affected by vitamins E and C. The findings of this study demonstrated that vitamin E and C ingestion can dramatically lower blood pressure and result in remission of insulin activity and fat profile.14Studies have demonstrated that vitamin E helps people with type 2 diabetes lower their blood pressure and blood glucose levels.15Of fact, some research have shown that vitamin E does not help patients' blood sugar levels.516In a study executed by Onyesom and colleagues, vitamin METHODS According to a standard survey responses questions about diabetes, 6where you live and your food were asked.The patient's information and measured vitamin E levels were put into a checklist, and finally the results were evaluated.

Table No . -1- Table 2: Outcomes of hepatic enzyme testing in patients with diabetes . Test
ALT(IU/l) AST(IU/l)

Table 3 :
The correlation with vitamin E levels and dietary vitamin E has been demonstrated using Pearson's coefficient.Parameters quantity of vitamin EAmount of food E vitamin