A study of some antioxidants and biochemical variables in the sera of breast cancer patients from southern Iraq after receiving chemotherapy and radiotherapy

Abstract

In order to investigate the case of a change in antioxidants and some of biochemical changes in the serum of   breast cancer patients by receiving chemotherapy and radiation therapy, it have been measure the level of anti-oxidants and the level of blood fat in the serum.  The study included 60 female suffering from breast cancer  They were treated at  AL-Shifa Oncology Centre and Hospital, radiation and nuclear medicine in Misan province (treatment chemical therapy group(1) = 30 and a radiation therapy group(2) = 30) in addition to the 29 female from collage of medicine-Misan healthy represent the control group, for the period from October 2015 until February  2016.

  The level of MDA , was significant increase in the chemotherapy group                (P ≤ 0.05) and it was significantly decreased in the radiotherapy group (P ≤0.001) compared with the control group. And the level of vitamin A, was significant increase in two groups of chemotherapy (P ≤ 0.05) and radiotherapy group (P ≤ 0.05) compared with the control group. The level of vitamin C, was significant increase   in a chemotherapy  (P ≤ 0.05)  and radiotherapy group (P ≤ 0.05)  compared with the control group.

  The level of cholesterol was  significant increase in the chemotherapy group        (P ≤ 0.05) and radiotherapy group (P ≤ 0.05) compared with the control group. And  the level of triglycerides was significant decrease in the chemotherapy group (P ≤ 0.05) and radiotherapy group (P ≤ 0.05) compared with the control group.