Effect of The Aqueous Extract of Rocket( Eruca sativa L.) Leaves on the Histological Structure of Some Organs in Male Mice

Abstract

In this study we have assessed the effect of the hot aqueous extract of (Eruca
sativa) leaves on the histological structure of (Kidney, liver and spleen) in male
albino mice. Two experimental groups were used in this study(250 and
500mg/kg body weight).The extract was given orally for 30 days. There was a
significant increase in weighs of the liver for the two treated groups as compared
with control and only the 500mg/kg group shows a significant increase in weighs
of kidney. The histological study for the treated groups shows hypertrophy of the
hepatic cells with the accumulation of glycoprotein granules. Sections of the
spleen revealed expansion of the white pulp and red pulp areas in addition to the
presence of megakaryocytes and haemosedirosis in some areas. While sections
of the kidney did not show a remarkable changes. A detection for some active
ingredients found in the plant extract reveals the presence of (saponins ,alkaloids,
flavenoids, tannins and glycosides).