Preparation and characterization of some new derivatives 6-bromo-2-phenylquinoline-4-carboxylic acid

Abstract

This   research includes  the   preparation of  thirty four  new    derivatives      of 6-bromo-2-phenylquinoline-4-carboxylic acid , and  these  derivatives were  characterized by their melting point      (C.H.N.S) Analysis , (¹H-NMR) spectrum, mass spectrum, (FT-IR) spectrum.                                                           The synthesized compounds were  divides into :-

1- Preparation of 6-bromo-2-phenylquinoline-4-carboxylic acid   

2- Preparation of 6-bromo-2-phenylquinoline-4-carboxyl chloride

3-- Preparation of ethyl 6-bromo-2-phenylquinoline-4-carboxylate

4- Preparation of 2-(6-bromo-2-phenylquinoline-4  carboxamido) benzoic acid

5- Preparation of N-acetyl 6-bromo-2-phenylquinoline-4-carboxamide

6- Preparation of 6-bromo-2-phenylquinoline-4-carbohydrazide